每周视点：蓝耳病等其他猪病的研究进展 Progress on PRRS and Other Pig Health I...

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WeeklyOverview: Progress on PRRS and Other Pig Health Issues

  每周视点：蓝耳病等其他猪病的研究进展

GLOBAL - Porcine Reproductive andRespiratory Syndrome (PRRS) is among the world's most costly pig diseases andit is proving challenging to control, particularly because of the differentviral strains that exist. New research sheds some light on how the strainsimpact the pig's immune system in different ways. Hungary has been declaredfree of Classical Swine Fever and in the US, a new Bill will further tighten upon antibiotic use in animal agriculture.

简介：猪繁殖与呼吸综合症（PRRS）是世界上损失最大，同时也是最难控制的猪病，特别是有不同毒株的存在。最新的研究揭示了毒株如何以不同的方式影响免疫系统。匈牙利宣布彻底消灭了典型猪瘟，美国新的草案条例进一步加强管制抗生素在畜牧业上的使用。

Porcine Reproductive and RespiratorySyndrome (PRRS) is proving to be a challenging disease to bring under control –and very costly to the industry.

猪繁殖与呼吸综合症（PRRS）被证明是最难控制的疾病，同时在畜牧业中损失也是相当大的。

A recent study from theUS puts the annual cost there at US$664 million – more than in 2005 and with agreater share of this cost in the breeding herd as some progress has been madein controlling the disease in growing pigs

. The US National Pork Board in the UShas suggests that, by developing a better understanding of themechanisms PRRS virus uses to evade the immune system, scientistswill be in a much better position to deal with the infection,

Thesyndrome affects the reproductive performance of breeding sows and slows growthrates among grower pigs and is considered the most costly disease facing NorthAmerican pork producers

. Several strategies have been used toaddress PRRS including the establishment of more than two dozen regional PRRSelimination projects across the US.

美国猪肉协会表明，通过进一步的了解PRRS病毒逃避机体免疫系统的机制，会对科学家研究控制PRRS 感染帮助很大。

美国最近的一项关于花费6.64美元关于种猪群的研究，在生长育肥猪的疾病控制上取得了一些进展。

该综合症主要影响母猪的繁殖性能和生长育肥猪的生长速度，被认为是北美猪肉生产者的头号敌人。

对此美国采取了很多策略处理PRRS，包括建立超过24个区域的PRRS消灭计划。

The Board’s Dr Lisa Becton acknowledges itis hard to know exact numbers but many farms see recurring issues with PRRS -both in terms of new outbreaks and the recurrence of the disease on farms thathad previously been affected.

该协会的LisaBecton博士承认很难估计具体数字，但是有很多农场反映PRRS有反复性的规律，包括新的变异疫情还有之前感染过的再次复发。

She highlights that we do not yet fullyunderstand the mechanism that the virus uses to evade the pig’s immune system,which is one reason why vaccinating against one strain of the virus does notconfer complete or absolute protection against any other strain.

她强调我们尚未完全了解病毒是如何逃避免疫系统的机制，这也是为什么免疫接种后不能对某一种毒株或其他毒株产生完全免疫保护。

New research from Spain may help to shedsome light on these issues. Researchers of CReSA have demonstrated that inoculation with different PRRS virusstrains result in different virological and immunological outcomes andin different degrees of homologous and heterologous protection.

来自西班牙的研究可能对此做出解释，来自CRESA的研究者证实接种不同的PRRS毒株会产生不同的病毒学和免疫学效果，和不同程度的同源和异源保护。

Their results indicate that almost oppositemodels of immune response to the virus could exist, depending on the strain:one based mainly in the development of neutralising antibodies (NA) with lowvirus-specific interferon-γ secreting cell (IFN-γ-SC) responses, the other withpredominance of IFN-γ responses and a poor development of NA.

结果表明可能存在几乎相反的免疫模式。接种毒株后，一种会产生免疫抗体和低特异性的干扰素生。其他的会产生高强度的干扰素和低效价的中和抗体。

In virological terms - but not based onzootechnical parameters - heterologous immunity sometimes could be moreefficacious than the homologous one, the CReSA research team added

.在病毒学方面，不是机遇畜牧生产实际数据上，不同源的免疫效果好于同源免疫。

EU Member States have voted to remove theremaining health restrictions forclassical swine fever (CSF)in wild boar in Hungary. Surveillance carried out in 2012 and early 2013 hasshown that the disease has been eradicated.

欧盟成员过投票决定去除对匈牙利猪瘟野毒的限制，该国监控表示，在2012年和2013年初猪瘟已经被根除。

Finally, in health-related news, threeUS senators have introduced the bipartisanAntimicrobial Data Collection Bill,which aims to increase the data collected by the FDA on antibiotic use in farmanimals. The news has been applauded by Pew Charitable Trusts as a move towardsending antibiotic use for growth promotion.

     最后，关于卫生的新闻，三位美国参议员引入两党抗生素收集草案，旨在通过FDA收集在农场中使用的抗生素，该草案呗皮尤慈善信托基金所支持以结束抗生素的滥用。

007畜牧

加油 继续哦

w65148871

007畜牧 发表于 2013-5-20 08:41
加油 继续哦

好的 ，，，，美女