|
石放雄,博士,教授,博士生导师。南京农业大学家畜繁殖学研究室主任,《畜牧与兽医》杂志社主编,江苏省“333高层次人才培养工程”中青年科学技术带头人,南京市江宁区科技咨询委员会专家委员。1979年考入浙江农业大学畜牧本科,1983年取得学士学位并考取攻读浙江农业大学动物生理生化专业硕士学位,1986年获得硕士学位后留校任教,1994年晋升为副教授并任浙江大学动物科学学院生理学和药理学教研室主任。1996年1月获日本国政府的资助赴东京农工大学兽医系家畜生理学教室进修,并于1997年4月考取博士课程。其中曾于1999年1月至1999年12月在日本国国立传染病学研究所任合作研究员。2001年3月获得博士学位,于2001年4月赴美国达拉斯德克萨斯大学西南医学研究中心从事博士后研究工作,并于2001年8月转至美国洛杉矶加利福尼亚州州立大学生物科学系继续博士后研究工作。2004年6月回国加盟南京农业大学动物科技学院。目前主要从事与生殖相关的主效基因的表达和调控,生殖系统的细胞信号传导,动物生殖生理与调控,生殖毒理学等研究工作。1999年以来,发表SCI收录论文20多篇。是上海外语教育出版社新牛津英汉双解词典的畜牧,渔业的专业审定人。
发表论文:
SCI杂志
1 Wang Z, Shi F, Jiang Y, Lu L, Watanabe G, Taya K. Changes of cyclic AMP levels and phosphodiesterase activities in the rat ovary. Journal of Reproduction and Development. 2007; 53(4):717-725. (PMID: 17380041).
2 Meng C, Shi F, Huang R, Liu G, Watanabe G, Taya K. Cellular localization of inhibin alpha-subunit, PKB/Akt and FoxO3a proteins in the ovary of minipigs. Journal of Reproduction and Development. 2007; 53(2): 229-236. (PMID: 17132910).
3 Huang R, Shi F, Lei T, Song Y, Hughes CL, Liu G. Effect of the isoflavone genistein against galactose-induced cataracts in rats. Experimental Biology and Medicine. 2007; 232:118-125. (PMID: 17202592).
4 Wang Z, Shi F. Phosphodiesterase 4 and compartmentalization of cyclic AMP signaling. Chinese Science Bulletin. 2007; 52:34-46.
5 潘玲梅,王恬,石放雄. 肌卫星细胞激活和补给的分子调控与肌肉疾病. 生物化学与生物物理进展 2006; 33(9):811-815.
6 Huo YJ, Wang T, Xu RJ, Macdonald S, Liu G, Shi F. Dietary insulin affects leucine aminopeptidase, growth hormone, insulin-like growth factor I and insulin receptors in the intestinal mucosa of neonatal pigs. Biology of the Neonate. 2006; 89:265-73. (PMID: 16479091).
7 Liu G, Shi F (equal contribution), Blas-Machado U, Yu R, Davis VL, Foster WG, Magoffin DA, Hughes CL. Dietary Galactose Inhibits GDF-9 Mediated Follicular Development in the Rat Ovary. Reproductive Toxicology 2006; 21:26-33. (PMID: 16105726).
8 李学斌, 谢 庄, 石放雄. FOXO 蛋白的修饰与细胞凋亡和癌变.生物化学与生物物理进展 2005; 32:600-606.
9 Liu G, Shi F, Blas-Machado U, Duong Q, Davis VL, Foster WG, Hughes CL. Ovarian effects of high lactose diet in the female rat. Reproduction, Nutrition, Development 2005; 45:185-192. (PMID: 15954229).
10 Wang T, Huo Y, Shi F, Xu R, Hutz RJ. Effects of Intrauterine Growth Retardation on Development of the Gastrointestinal Tract in Neonatal Pigs. Biology of the Neonate 2005; 88:66-72. (PMID: 15785017).
11 Shi F, Perez E, Wang T, Peitz B, Lapolt PS. Stage and Cell-Specific Expression of Soluble Guanylyl Cyclase alpha and beta Subunits, cGMP-Dependent Protein Kinase I-alpha and I-beta, Cyclic Nucleotide-Gated Channel Subunit-1 in the Rat Testis. Journal of Andrology 2005; 26:258-263. (PMID: 15713832).
12 Shi F, Stewart RL, Perez E, Chen JY, LaPolt PS. Cell-specific expression and regulation of soluble guanylyl cyclase alpha and beta subunits in the rat ovary. Biology of Reproduction 2004; 70:1552-1561. (PMID: 14749300).
13 Shi F, LaPolt PS. Relationship between FoxO1 protein levels and follicular development, atresia, and luteinization. Journal of Endocrinology 2003; 179:195-203. (PMID: 14596671).
14 Shi F, Petroff BK, Herath CB, Ozawa M, Watanabe G and Taya K. Serous cysts are a benign component of the cyclic ovary in the guinea pig with an incidence dependent upon inhibin bioactivity. Journal of Veterinary Medical Science 2002; 64(2):129-135. (PMID: 11913549).
15 Akagi S, Shi F, Kaneko H, Nakanishi Y, Watanabe G, Tsonis CG and Taya K. Ovarian response and hormonal profiles in heifers after immunization and re-immunization against the inhibin alpha-subunit. Journal of Reproduction and Development 2002; 48(6): 599-605.
16 Petroff BK, Gao X, Ohshima K, Shi F, Son D, Roby KF, Rozman KK, Watanabe G, Taya K and Terranova P. Effects of 2,3,7,8-tetrachlorodibenzo-pdioxin (TCDD) on serum inhibin concentrations and inhibin immunostaining during follicular development in female Sprague-Dawley rats. Reproduction Toxicology 2002; 16:97-105. (PMID: 11955940).
17 Tohei A, Shi F, Ozawa M, Imai K, Takahashi H, Shimohira T, Watanabe G and Taya K. Dynamic changes in plasma concentrations of gonadotropin, inhibin, estradiol and progesterone in cows with ultrasound-guided follicular aspiration. Journal of Veterinary Medical Science 2001; 63:45-50. (PMID: 11217062).
18 Ozawa M, Shi F, Watanabe G, Suzuki AK and Taya K. Regulatory role of inhibin in follicle-stimulating hormone secretion and folliculogenesis in the guinea pig. Journal of Veterinary Medical Science 2001; 63: 1091-1095. (PMID: 11714024).
19 Shi F, Ozawa M, Komura H, Watanabe G, Tsonis CG, Suzuki AK and Taya K. Induction of superovulation by inhibin vaccine in cyclic guinea pigs. Journal of Reproduction and Fertility 2000; 118:1-7. (PMID: 10793620)
20 Shi F, Mochida K, Ogura A, Matsuda J, Suzuki O, Watanabe G, Hutz RJ, Tsonis CG, Suzuki AK and Taya K. Follicle selection in guinea pigs with active immunization against inhibin alpha-subunit. Life Sciences 2000; 66:2489-2497. (PMID: 10894091).
21 Shi F, Mochida K, Suzuki O, Matsuda J, Ogura A, Tsonis CG, Watanabe G, Suzuki AK and Taya K. Development of superovulated embryos in guinea pigs with active immunization against inhibin alpha-subunit. Endocrine Journal 2000; 47(4): 451-459. (PMID: 11075726).
22 Shi F, Watanabe G, Trewin AL, Hutz RJ and Taya K. Localization of ovarian inhibin/activin subunits in follicular dominance during the estrous cycle of guinea pigs. Zoological Science 2000; 17(9):1311-1320.
23 Shi F, Mochida K, Matsuda J, Ogura A, Suzuki O, Ozawa M, Watanabe G, Suzuki AK and Taya K. Ovarian localization of immunoglobulin G and inhibin alpha-subunit in guinea pigs following passive immunization against the inhibin a-subunit. Journal of Reproduction and Development 2000;46:293-299.
24 Shi F, Ozawa M, Komura H, Yang P, Trewin AL, Hutz RJ, Watanabe G and Taya K. Secretion of ovarian inhibin and its physiologic roles in the regulation of follicle-stimulating hormone secretion during the estrous cycle of the female guinea pig. Biology of Reproduction 1999; 60:78-84. (PMID: 9858489).
25 .........
Medline杂志:
1 Wang Z, Jiang Y, Lu L, Huang R, Hou Q, Shi F. Molecular mechanisms of cyclic nucleotide-gated ion channel gating. Journal of Genetics and Genomics, 2007; 34(6):477-485. (PMID:17601606)
2 王皓,葛津瑶,周振琪,王正朝,石放雄。口服丙烯酰胺对雄性大鼠生长发育及生殖机能的影响。中华男科学杂志,2007,13(6):492-497. (PMID: 17615970).
3 Zhou Z, Wang T, Pan L, Huang R, Shi F. FoxO4 is the main forkhead transcriptional factor localized in the gastrointestinal tracts of pigs. Journal of Zhejiang University Science 2007; 8:39-44 (PMID: 17173361).
科研项目:
1. 南京农业大学高层次人才引进基金,“功能蛋白基因表达和调控”,2004年6月开始。
2. 国家自然科学基金面上项目(编号:30571335),“FOXO蛋白在大鼠和猪卵巢中的定位和颗粒细胞成熟中的作用”,2006年1月至08年12月。
3. 教育部留学回国人员科研启动基金,“FOXO转录因子在大鼠卵巢颗粒细胞中的表达和调控机制”,2005年7月至08年7月。
4. 江苏省研究生培养创新工程,“环核苷酸门控离子通道(CNG)对高产奶牛卵巢功能及其Ca2+的调控”,2006年9月至09年7月。
5. 国家自然科学基金面上项目(编号:30771553),“母猪卵巢卵泡发育过程中FOXO蛋白,磷酸二酯酶和CNG离子通道的调节机制”,2008年1月至10年12月。
荣誉及获奖:
1. 1986年至88年以第一主持人完成的浙江省科委项目“奶牛妊娠,发情及卵巢疾病快速诊断盒的研制”获浙江省人民政府颁发的1989年度科学技术进步奖四等奖, 于1989年至92年以第一主持人完成的“睾酮和孕酮的酶免疫分析法及其临床应用”获浙江省教育委员会颁发的1992-93年度科学技术进步奖三等奖。发表的系列研究论文于1991年获中国生理学会张锡钧基金会优秀论文奖.
2. 1995年获浙江农业大学大江园丁教学奖.
3. 2006年获南京农业大学动物科技学院溢多利育人奖.
4. 南京市江宁区科技咨询委员会委员(2007,1-).
5. <<畜牧与兽医>>杂志主编(2007,3-).
6. 英国杂志《The Open Andrology Journal》编委(2008,10-).
|
版权声明:本文内容来源互联网,仅供畜牧人网友学习,文章及图片版权归原作者所有,如果有侵犯到您的权利,请及时联系我们删除(010-82893169-805)。
|